GUCY2F Antibody - BSA Free

Immunohistochemistry: GUCY2F Antibody - BSA Free [NBP3-46155] - Immunohistochemistry of paraffin-embedded human heart tissue slide using (GUCY2F Antibody) at dilution of 1:50

Western Blot: GUCY2F Antibody - BSA Free [NBP3-46155] - Mouse heart tissue were subjected to SDS PAGE followed by western blot with (GUCY2F Antibody) at dilution of 1:600

• Reactivity: Hu, Mu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

GUCY2F Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit GUCY2F Antibody - BSA Free (NBP3-46155) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: guanylate cyclase 2F, retinal. (Uniprot# P51841)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GUCY2F
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 125 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for GUCY2F Antibody - BSA Free

• CYGF
• EC 4.6.1
• GC-F
• GC-FEC 4.6.1.2
• guanylate cyclase 2F, retinalRETGC-2
• Guanylate cyclase F
• Guanylyl Cyclase F
• GUC2DL
• GUC2Fguanylate cyclase 2D-like, membrane (retina-specific)
• GUCY2F
• RETGC2
• retinal guanylyl cyclase 2
• Rod outer segment membrane guanylate cyclase 2
• ROS-GC2
• ROS-GC2RetGC-2

Background

The GUCY2F gene encodes a retinal guanylyl cyclase 2 single-pass type 1 membrane protein that plays a significant functional role in the rods and cones of photoreceptors. Its coded proteins are 1,108 amino acids long at a mass of approximately 124 kDA. It is thought to be involved in the resynthesis of cGMP which is required for recovery of a dark state after light activation of the visual signal transduction cascade (phototransduction). The GUCY2F gene participates is purine metabolism, relaxin pathway, phototransduction, and the CRHR pathway. Its known to interact with various genes such as GUCA1B, GUCA1A, GUCA1C, PDE11A, and PDE4A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GUCY2F