Granzyme M Antibody (C2) - BSA Free

• Reactivity: Hu
• Applications: WB
• Clone: C2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

Granzyme M Antibody (C2) - BSA Free Summary

• Description: Novus Biologicals Mouse Granzyme M Antibody (C2) - BSA Free (NBP3-41477) is a monoclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Immunized with recombinant Human Granzyme M (Uniprot#: P51124; Ile26-Ala257 (Uniprot#: P51124)
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: GZMM
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.01-2ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.01M PBS, pH7.4, 50% glycerol
• Preservative: 0.05% Proclin 300
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for Granzyme M Antibody (C2) - BSA Free

• EC 3.4.21
• EC 3.4.21.-
• granzyme M (lymphocyte met-ase 1)
• granzyme M
• Hu-Met-1
• LMET1
• lymphocyte met-ase 1
• Met-1 serine protease
• MET1met-ase
• Met-ase
• Natural killer cell granular protease

Background

The GZMM gene encodes a 257 amino acid long, 27 kDA granzyme M protein that cleaves peptide substrates after methionine, leucine, and norleucine. In doing so, it encourages caspase activation and apoptosis of target cells. GZMM has been investigated for its role in arrhythmogenic right ventricular dysplasia as it participates in the immune system, alternative complement activation, and granzyme pathways. It is known to interact with genes CASP3, DFFA, EZR, NPM1, and PAK2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GZMM