Granzyme M Products

Description

The GZMM gene encodes a 257 amino acid long, 27 kDA granzyme M protein that cleaves peptide substrates after methionine, leucine, and norleucine. In doing so, it encourages caspase activation and apoptosis of target cells. GZMM has been investigated for its role in arrhythmogenic right ventricular dysplasia as it participates in the immune system, alternative complement activation, and granzyme pathways. It is known to interact with genes CASP3, DFFA, EZR, NPM1, and PAK2.

Bioinformatics

Entrez	3004 Human
Uniprot	AAH25701.1 Human NM_005317 Human NP_005308 Human
Product By Gene ID	3004
Alternate Names	EC 3.4.21 EC 3.4.21.- granzyme M (lymphocyte met-ase 1) granzyme M HU-Met-1 Hu-Met-1 LMET1 lymphocyte met-ase 1 Met-1 serine protease MET1met-ase Met-ase Natural killer cell granular protease

Research Areas for Granzyme M

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Apoptosis
Cancer
Immunology
Innate Immunity
Tumor Suppressors