Granzyme M Antibody (4D11) - Azide and BSA Free

Western Blot: Granzyme M Antibody (4D11) [H00003004-M03] - detection against Immunogen (38.1 KDa) .

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 4D11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Granzyme M Antibody (4D11) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: GZMM (NP_005308, 85 a.a. ~ 193 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. DSPGLTFHIKAAIQHPRYKPVPALENDLALLQLDGKVKPSRTIRPLALPSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMVCL
• Specificity: granzyme M (lymphocyte met-ase 1)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: GZMM
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Granzyme M Antibody (4D11) - Azide and BSA Free

• EC 3.4.21
• EC 3.4.21.-
• granzyme M (lymphocyte met-ase 1)
• granzyme M
• Hu-Met-1
• LMET1
• lymphocyte met-ase 1
• Met-1 serine protease
• MET1met-ase
• Met-ase
• Natural killer cell granular protease

Background

Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and Met-ase, also known as granzyme M.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Granzyme M Antibody (H00003004-M03)(1)

Publication using H00003004-M03

• Schiffer S, Letzian S, Jost E et al. Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells. Cancer Lett. 2013-08-22 [PMID: 23973499]

Bioinformatics

• Gene Symbol: GZMM
• Entrez:
  • 3004(Human)
• OMIM:
  • 600311(Human)
• Uniprot:
  • NP_005308(Human)