Granulysin Antibody (DH2) [PE]

Product Discontinued

Granulysin Antibody (DH2) [PE] Summary

• Immunogen: The immunogen for this antibody was Granulysin.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: GNLY
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1:10-1:1000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500

Reactivity Notes

This antibody is reactive to Human.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS (pH 7.2) with 0.1% gelatin
• Preservative: 0.05% Sodium Azide
• Concentration: 0.05 mg/ml
• Purity: Protein A or G purified

Alternate Names for Granulysin Antibody (DH2) [PE]

• D2S69Elymphocyte-activation gene 2
• GNLY
• Granulysin
• LAG2
• LAG-2
• Lymphokine LAG-2
• Lymphokine
• NKG5
• NKG5519
• Protein NKG5
• TLA519
• TLA519T-cell activation protein 519
• T-lymphocyte activation gene 519

Background

The DH2 monoclonal antibody reacts with human granulysin, a protein involved in the cytolytic pathway. Granulysin is a member of the saposin-like protein (SAPLIP) family. Two proteins 9 and 15kDa are thought to be post translation modified versions of the 15kDa protein with a change in confirmation. Granulysin is found in NK and activated T cells and the expression is confined to the cytolytic granules which also contains perforin and granzyme. Granulysin with perforn are suspected to function synergistically to kill bacteria and induce apoptosis in nucleated cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNLY