Granulysin Products

Description

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Bioinformatics

Entrez	10578 Human
Uniprot	NM_006433 Human NP_006424 Human NP_006424.2 Human AAH23576 Human
Product By Gene ID	10578
Alternate Names	Protein NKG5 Lymphokine LAG-2 T-lymphocyte activation gene 519 LAG-2 D2S69Elymphocyte-activation gene 2 NKG5519 TLA519T-cell activation protein 519 LAG2 granulysin

Diseases related to Granulysin

Discover more about diseases related to Granulysin.

Neoplasms
Tuberculosis
Malignant Neoplasms
Infective Disorder
Bacterial Infections
Hiv Infections
Inflammation
Tuberculosis, Pulmonary
Immunologic Deficiency Syndromes
Cell Invasion
Carcinoma
Stevens-johnson Syndrome
Infection By Cryptococcus Neoformans
Communicable Diseases
Lymphoma
Leprosy
Hepatitis B
Hepatitis
Mycobacterium Infections

Pathways for Granulysin

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Immune Response
Exocytosis
Cell Death
Pathogenesis
Cell Activation
Secretion
Localization
T Cell Activation
Cytolysis
Killer Activity
Chemotaxis
Cytokine Production
Granulysin Production
Cell Adhesion
Transport
Hypersensitivity
Inflammatory Response
Translation
Innate Immune Response
Cell Proliferation

Research Areas for Granulysin

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Adaptive Immunity
Immunology

PTMs for Granulysin

Learn more about PTMs related to Granulysin.

Cleavage
Phosphorylation
Reduction

Bioinformatics Tool for Granulysin

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