GRAF Antibody

Images

 
Western Blot: GRAF Antibody [NBP2-16732] - Sample (30 ug of whole cell lysate) A: HepG2 7. 5% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

GRAF Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human GRAF. The exact sequence is proprietary.
Localization
Cell junction; focal adhesion (By similarity); Cytoplasm; cytoskeleton (By similarity)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
ARHGAP26
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
92 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Chicken (87%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for GRAF Antibody

  • FLJ42530
  • GRAFGTPase regulator associated with focal adhesion kinase pp125(FAK)
  • KIAA0621rho GTPase-activating protein 26
  • Oligophrenin-1-like protein
  • OPHN1L1
  • OPHN1LGTPase regulator associated with focal adhesion kinase
  • Rho GTPase activating protein 26
  • Rho-type GTPase-activating protein 26

Background

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ARHGAP26
Uniprot