GPR39 Antibody (189702) [Alexa Fluor™ Plus 405]

• Clone: 189702
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 405

GPR39 Antibody (189702) [Alexa Fluor™ Plus 405] Summary

• Specificity: Detects human GPR39. Stains human GPR39-transfected cells but not irrelevant transfectants.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

G Protein-coupled Receptor 39 (GPR39) is a seven-transmembrane glycoprotein and a member of the Ghrelin receptor family. GPR39 is expressed in the stomach, small intestine and areas of the brain including the hypothalamus; its ligand is the Ghrelin-associated peptide, Obestatin. Obestatin decelerates gastric emptying and decreases intestinal contractility in mice, counteracting the effects of Ghrelin. GPR39 has not been shown to be internalized upon ligand binding. Extracellular loops of human GPR39 show 80% amino acid identity with mouse GPR39.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.