GNPDA1 Antibody

Product Discontinued

GNPDA1 Antibody Summary

• Immunogen: Antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human GNPDA1. The immunogen is located within the last 50 amino acids of GNPDA1.
• Specificity: GNPDA1 is predicted to not cross-react with GNPDA2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GNPDA1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
  • Western Blot 1:100-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GNPDA1 Antibody

• EC 3.5.99.6
• GlcN6P deaminase 1
• glucosamine-6-phosphate deaminase 1KIAA0060HLNGNPIGNPDA
• glucosamine-6-phosphate isomerase 1
• glucosamine-6-phosphate isomerase
• GNP1
• GNPDA 1
• GPI
• oscillin

Background

Glucosamine-6-phosphate deaminase (GNPDA) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA1 is one of two mammalian glucosamine-6-phosphate deaminases that are thought to have arisen though gene duplication, with the GNPDA2 protein closer in structure and activity to the E. coli enzyme. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2. GNPDA1 is predicted to not cross-react with GNPDA2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNPDA1
• Uniprot:
  • AAC05123(Human)