Glycine N-Methyltransferase/GNMT Antibody (691305) [DyLight 594]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 691305
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 594

Glycine N-Methyltransferase/GNMT Antibody (691305) [DyLight 594] Summary

• Immunogen: E. coli-derived recombinant human Glycine N-methyltransferase/GNMT
  Met1-Asp295
  Accession # Q14749
• Specificity: Detects human Glycine N-methyltransferase/GNMT in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GNMT
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Glycine N-Methyltransferase/GNMT Antibody (691305) [DyLight 594]

• EC 2.1.1.20
• Glycine NMethyltransferase
• Glycine N-Methyltransferase
• GNMT

Background

GNMT is encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. The encoded protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNMT