Human Glutathione S-Transferase pi 1/GSTP1 ELISA Kit (Chemiluminescence)

Human Glutathione S-Transferase pi 1/GSTP1 ELISA Kit (Chemiluminescence) [NBP3-25938] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 0.47 - 30 ng/mL
• Sensitivity: 0.28 ng/mL

Human Glutathione S-Transferase pi 1/GSTP1 ELISA Kit (Chemiluminescence) Summary

• Description: Assay Time: 4.5h
• Specificity: This kit recognizes Human Glutathione S-Transferase pi 1/GSTP1 in samples. No significant cross-reactivity or interference between Human Glutathione S-Transferase pi 1/GSTP1 and analogues was observed.
• Standard Curve Range: 0.47 - 30 ng/mL
• Sensitivity: 0.28 ng/mL
• Assay Type: Sandwich-CLIA
• Inter-Assay: CV% < 12.00
• Intra-Assay: CV% < 11.49
• Spike Recovery: 87 - 115%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Chemiluminescence)
• Gene: GSTP1

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Glutathione S-Transferase pi 1/GSTP1 ELISA Kit (Chemiluminescence)

• deafness, X-linked 7
• DFN7
• EC 2.5.1.18
• FAEES3
• fatty acid ethyl ester synthase III
• glutathione S-transferase P
• Glutathione STransferase pi 1
• Glutathione S-Transferase pi 1
• GST class-pi
• GST3DFN7
• GSTP
• GSTP1
• GSTP1-1
• PI

Background

GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13 , is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: GSTP1