GHRHR Antibody (2765A) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 2765A
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 350

GHRHR Antibody (2765A) [Alexa Fluor® 350] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Human GHRHR synthetic peptide sequences within the first extracellular loop of the protein
  
  Accession # Q02643
• Specificity: Detects human GHRHR in direct ELISAs.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for GHRHR Antibody (2765A) [Alexa Fluor® 350]

• GHRFR
• GHRH receptor
• GHRHR
• GRF receptor
• GRFR
• growth hormone releasing hormone receptor
• Growth hormone-releasing factor receptor
• growth hormone-releasing hormone receptor
• IGHD1B
• Little

Background

GHRHR is a GPCR that binds growth hormone-releasing hormone that is expressed in the pituitary.  Significant amounts of GHRHR are also found in the hypothalamus, kidney, and placenta.  GHRH regulates the secretion of growth hormone that controls the metabolism and growth of every tissue through its binding with GHRHR.  Malfunction in GHRHR signaling is associated with abnormal growth.  GHRHR is a therapeutic target against dwarfism, gigantism, lipodystrophy, and certain cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.