GHRHR Antibody (1037308) [Janelia Fluor® 646]

• Reactivity: Hu
• Applications: WB
• Clone: 1037308
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 646

GHRHR Antibody (1037308) [Janelia Fluor® 646] Summary

• Immunogen: Human GHRHR synthetic peptide
  Accession # Q02643
• Specificity: Detects human GHRHR in direct ELISAs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for GHRHR Antibody (1037308) [Janelia Fluor® 646]

• GHRFR
• GHRH receptor
• GHRHR
• GRF receptor
• GRFR
• growth hormone releasing hormone receptor
• Growth hormone-releasing factor receptor
• growth hormone-releasing hormone receptor
• IGHD1B
• Little

Background

GHRHR belongs to the glucagon family and is produced in the hypothalamus as a preproprotein. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.