Recombinant Human GGPS1 Protein

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SDS-Page: Recombinant Human GGPS1 Protein [NBP1-48358] - 15 % SDS-PAGE (3ug)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human GGPS1 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-300 of Human GGPS1

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEKTQETVQR ILLEPYKYLL QLPGKQVRTK LSQAFNHWLK VPEDKLQIII EVTEMLHNAS LLIDDIEDNS KLRRGFPVAH SIYGIPSVIN SANYVYFLGL EKVLTLDHPD AVKLFTRQLL ELHQGQGLDI YWRDNYTCPT EEEYKAMVLQ KTGGLFGLAV GLMQLFSDYK EDLKPLLNTL GLFFQIRDDY ANLHSKEYSE NKSFCEDLTE GKFSFPTIHA IWSRPESTQV QNILRQRTEN IDIKKYCVHY LEDVGSFEYT RNTLKELEAK AYKQIDARGG NPELVALVKH LSKMFKEENE

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
GGPS1
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human GGPS1 Protein

  • 6E)-farnesyl diphosphate synthase
  • dimethylallyltranstransferase
  • EC 2.5.1.1
  • EC 2.5.1.10
  • EC 2.5.1.29
  • Farnesyl diphosphate synthase
  • Farnesyltranstransferase
  • geranylgeranyl diphosphate synthase 1
  • Geranylgeranyl diphosphate synthase
  • geranylgeranyl pyrophosphate synthase
  • geranyltranstransferase
  • GGPP synthase
  • GGPPS
  • GGPPS1farnesyltranstransferase
  • GGPPSase

Background

Geranylgeranyl pyrophosphate synthase isoform A, also known as GGPS1, is a member of the prenyltransferase family. Predominantly expressed in testis, heart and skeletal muscle, GGPS1 localizes to the cytoplasm and catalyzes the formation of geranylgeranyl pyrophosphate, a precursor of geranylgeranylated proteins and carotenoids. GGPS1 is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Recombinant human GGPS1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol GGPS1