GEFT Antibody (7A1) [DyLight 650]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clone: 7A1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

GEFT Antibody (7A1) [DyLight 650] Summary

• Immunogen: RhoA/RAC/CDC42 exchange factor - (Uniprot# Q86VW2)
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: ARHGEF25
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for GEFT Antibody (7A1) [DyLight 650]

• GEFTRAC/CDC42 exchange factor
• Guanine nucleotide exchange factor GEFT
• p63RhoGEFrho guanine nucleotide exchange factor 25
• Rac/Cdc42/Rho exchange factor GEFT
• Rho guanine nucleotide exchange factor (GEF) 25
• RhoA/RAC/CDC42 exchange factor
• RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT

Background

The Rho family of small GTPases act as molecular switches to control a wide range of cellular processes. Guanine nucleotide exchange factors (GEFs), like GEFT, activate Rho GTPases by accelerating GDP/GTP exchange (Souchet et al., 2002 [PubMed 11861769]).[supplied by OMIM]. Transcript Variant: This variant (1) represents the longer transcript (1).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ARHGEF25