Frizzled-5 Antibody

Images

 
Immunohistochemistry-Paraffin: Frizzled-5 Antibody [NLS4284] - Anti-FZD5 / Frizzled 5 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry-Paraffin: Frizzled-5 Antibody [NLS4284] - Analysis of anti-FZD5 / Frizzled 5 antibody with pancreas, Islets of Langerhans.
Immunohistochemistry-Paraffin: Frizzled-5 Antibody [NLS4284] - Analysis of anti-FZD5 / Frizzled 5 antibody with Synovium, Rheumatoid Arthritis at 24 ug/ml.
Immunohistochemistry-Paraffin: Frizzled-5 Antibody [NLS4284] - Analysis of anti-FZD5 / Frizzled 5 antibody with human lung, non-small cell carcinoma.
Immunohistochemistry-Paraffin: Frizzled-5 Antibody [NLS4284] - Anti-FZD5 / Frizzled 5 antibody IHC of human synovium, rheumatoid arthritis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, Mk, RbSpecies Glossary
Applications IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Frizzled-5 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human FZD5 / Frizzled 5.
Specificity
Human FZD5 / Frizzled 5. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ART5 (44%).
Predicted Species
Mouse (94%), Rat (94%), Porcine (94%), Rabbit (94%), Bovine (94%), Canine (94%), Monkey (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FZD5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin 24 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (94%), Elephant (94%), Marmoset (88%), Hamster (81%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Frizzled-5 Antibody

  • C2orf31
  • chromosome 2 open reading frame 31
  • DKFZP434E2135
  • frizzled (Drosophila) homolog 5
  • frizzled homolog 5 (Drosophila)
  • Frizzled5
  • Frizzled-5
  • Frz-5
  • FZ-5
  • FZD5
  • fzE5
  • HFZ5
  • MGC129692
  • seven-transmembrane receptor frizzled-5
  • Wnt receptor

Background

FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway. FZD5 has been reported to be expressed in fetal kidney, fetal and adult liver, fetal lung, and adult pancreas. ESTs have been isolated from bone, liver/spleen, placenta, and prostate libraries. FZD5 was cloned from a retina cDNA library.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol FZD5
Entrez