FKBP12.6 Antibody [Janelia Fluor® 525]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Janelia Fluor 525

FKBP12.6 Antibody [Janelia Fluor® 525] Summary

• Immunogen: E. coli-derived recombinant human FKBP12.6
  Met1-Glu108
  Accession # P68106
• Specificity: Detects human, mouse, and rat FKBP12.6 in Western blots. In Western blots, approximately 15% cross-reactivity with recombinant human FKBP12 and less than 1% cross-reactivity with recombinant human FKBP13 and FKBP25 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: FKBP1B
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for FKBP12.6 Antibody [Janelia Fluor® 525]

• 12.6 kDa FK506-binding protein
• calstabin 2,12.6 kDa FKBP
• EC 5.2.1.8
• FK506 binding protein 1B, 12.6 kDa
• FK506-binding protein 12.6
• FK506-binding protein 1B (12.6 kD)
• FK506-binding protein 1B
• FKBP12.6
• FKBP-12.6
• FKBP12.6h-FKBP-12
• FKBP1B
• FKBP-1B
• FKBP1L
• FKBP9
• Immunophilin FKBP12.6
• OTK4
• OTK4PPIase FKBP1B
• peptidyl-prolyl cis-trans isomerase FKBP1B
• PKBP1L
• PPIase
• rotamase

Background

The protein encoded by the FKBP1B gene is a member of the immunophilin protein family, which play a role in immunoregulationand basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolylisomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A.Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are twoalternatively spliced transcript variants of this gene encoding different isoforms. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FKBP1B