FKBP12.6 Products

Description

The protein encoded by the FKBP1B gene is a member of the immunophilin protein family, which play a role in immunoregulationand basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolylisomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A.Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are twoalternatively spliced transcript variants of this gene encoding different isoforms. (provided by RefSeq)

Bioinformatics

Entrez	2281 Human
Uniprot	AAH02614 Human NM_054033 Human NP_004107 Human
Product By Gene ID	2281
Alternate Names	12.6 kDa FK506-binding protein calstabin 2,12.6 kDa FKBP EC 5.2.1.8 FK506 binding protein 1B, 12.6 kDa FK506-binding protein 12.6 FK506-binding protein 1B (12.6 kD) FK506-binding protein 1B FKBP-12.6 FKBP12.6h-FKBP-12 FKBP-1B FKBP1L FKBP9 Immunophilin FKBP12.6 OTK4PPIase FKBP1B peptidyl-prolyl cis-trans isomerase FKBP1B PKBP1L PPIase rotamase Rotamase

Research Areas for FKBP12.6

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