FGF-17 Antibody (121630) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 121630
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

FGF-17 Antibody (121630) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human FGF-17
  Thr23-Thr216
  Accession # O60258
• Specificity: Detects human FGF-17 in direct ELISAs and Western blots. In direct ELISA, approximately 7% cross-reactivity with recombinant human (rh) FGF-5 is observed and no cross-reactivity with rhFGF-acidic, rhFGF-basic, rhFGF-4, rhFGF-6, rhFGF-7, rhF
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FGF-17 Antibody (121630) [Alexa Fluor® 405]

• FGF-13
• FGF17
• FGF-17
• fibroblast growth factor 17

Background

Fibroblast growth factors (FGFs) play multiple biological functions including angiogenesis, mitogenesis, cellular differentiation and wound repairing. All members of the FGF family have a conserved approximately 120 amino acid core with 30‑70% identity. Among FGF family members, FGF-17 is most similar to FGF-8 (60% sequence identity) and FGF-18 (50% sequence identity). The mRNA of FGF-17 was found in midgestation of embryo and multiple adult tissues, and is preferentially expressed in specific sites, such as embryonic brain, developing skeleton and arteries. Human FGF‑17 shares 98.6% amino acid (aa) sequence identity with mouse FGF‑17. Rat FGF‑17 shares 100% aa sequence identity with mouse FGF‑17.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.