FERMT3/URP2 Antibody

Western Blot: FERMT3/URP2 Antibody [H00083706-B01P] - Analysis of FERMT3 expression in transfected 293T cell line by FERMT3 polyclonal antibody. Lane 1: URP2 transfected lysate(72.93 KDa). Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: FERMT3/URP2 Antibody [H00083706-B01P] - Analysis of purified antibody to URP2 on HeLa cell. (antibody concentration 10 ug/ml)

Product Discontinued

FERMT3/URP2 Antibody Summary

• Immunogen: FERMT3 (NP_113659.3, 1 a.a. - 663 a.a.) full-length human protein. MAGMKTASGDYIDSSWELRVFVGEEDPEAESVTLRVTGESHIGGVLLKIVEQINRKQDWSDHAIWWEQKRQWLLQTHWTLDKYGILADARLFFGPQHRPVILRLPNRRALRLRASFSQPLFQAVAAICRLLSIRHPEELSLLRAPEKKEKKKKEKEPEEELYDLSKVVLAGGVAPALFRGMPAHFSDSAQTEACYHMLSRPQPPPDPLLLQRLPRPSSLSDKTQLHSRWLDSSRCLMQQGIKAGDALWLRFKYYSFFDLDPKTDPVRLTQLYEQARWDLLLEEIDCTEEEMMVFAALQYHINKLSQSGEVGEPAGTDPGLDDLDVALSNLEVKLEGSAPTDVLDSLTTIPELKDHLRIFRPRKLTLKGYRQHWVVFKETTLSYYKSQDEAPGDPIQQLNLKGCEVVPDVNVSGQKFCIKLLVPSPEGMSEIYLRCQDEQQYARWMAGCRLASKGRTMADSSYTSEVQAILAFLSLQRTGSGGPGNHPHGPDASAEGLNPYGLVAPRFQRKFKAKQLTPRILEAHQNVAQLSLAEAQLRFIQAWQSLPDFGISYVMVRFKGSRKDEILGIANNRLIRIDLAVGDVVKTWRFSNMRQWNVNWDIRQVAIEFDEHINVAFSCVSASCRIVHEYIGGYIFLSTRERARGEELDEDLFLQLTGGHEAF
• Specificity: URP2 - UNC-112 related protein 2,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: FERMT3
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against transfected lysate for Western Blot. Has also been used for immunofluoresence and ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for FERMT3/URP2 Antibody

• fermitin family member 3
• FERMT3
• KIND3
• KIND3fermitin family homolog 3 (Drosophila)
• Kindlin 3
• Kindlin-3
• MGC10966
• MIG-2
• MIG2B
• MIG2BURP2SF
• MIG2-like protein
• UNC-112 related protein 2
• UNC112C
• Unc-112-related protein 2
• URP2
• URP2fermitin family homolog 3
• URP2SF

Background

URP2 plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3(ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelialcells. Required for activation of integri

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for FERMT3/URP2 Antibody (H00083706-B01P)(1)

Publication using H00083706-B01P

• Feng C, Li YF, Yau YH et al. Kindlin-3 mediates integrin alphaLb2 outside-in signaling and it interacts with the scaffold protein receptor for activated-C kinase 1 (RACK1). J Biol Chem. 2012-02-10 [PMID: 22334666]

Bioinformatics

• Gene Symbol: FERMT3
• Entrez:
  • 83706(Human)
• Uniprot:
  • NP_113659.3(Human)