FCRL4/FcRH4/IRTA1 Antibody (A1) - BSA Free

Flow Cytometry: FCRL4/FcRH4/IRTA1 Antibody (A1) [NBP3-11836] - Multicolor surface staining of human lymphocytes stained using anti-human CD19 (LT19) PE antibody (20 ul reagent / 100 ul of peripheral whole blood) and anti-human CD307d (A1) purified antibody (15 ug/ml, GAM-APC).

• Reactivity: Hu
• Applications: Flow, IHC
• Clone: A1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

FCRL4/FcRH4/IRTA1 Antibody (A1) - BSA Free Summary

• Description: Novus Biologicals Mouse FCRL4/FcRH4/IRTA1 Antibody (A1) - BSA Free (NBP3-11836) is a monoclonal antibody validated for use in IHC and Flow. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Clone A1 was used by HLDA to establish CD designation.
• Immunogen: DNA-immunization followed by a boost with FCRL4/FcRH4/IRTA1-transfected cells
• Specificity: The mouse monoclonal antibody A1 recognizes an epitope within extracellular domain of FCRL4/FcRH4/IRTA1, a transmembrane glycoprotein expressed mainly on memory B cells.
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCRL4
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 2-5 ug/ml
  • Immunohistochemistry
  • Immunohistochemistry-Frozen

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Phosphate buffered saline (PBS), pH 7.4
• Preservative: 15mM Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for FCRL4/FcRH4/IRTA1 Antibody (A1) - BSA Free

• CD307d antigen
• CD307d
• Fc receptor homolog 4
• Fc receptor-like 4
• FcRH4
• FCRH4Fc receptor-like protein 4
• FCRL4
• FcR-like protein 4
• hIFGP2
• IFGP family protein 2
• IFGP2
• IGFP2
• Immune receptor translocation-associated protein 1
• immunoglobulin superfamily Fc receptor, gp42
• immunoglobulin superfamily receptor translocation associated 1
• IRTA1
• IRTA1MGC150523
• MGC150522

Background

FCRL4/FcRH4/IRTA1 is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITIM motifs and one ITSM motif in its cytoplasmic domain. FCRL4/FcRH4/IRTA1 is expressed mainly on the surface of memory B cells in mucosa-associated lymphoid tissues. It binds to aggregated immunoglobulin molecules (IgA, IgG). Defects of FCRL4/FcRH4/IRTA1 may play a role in HIV-induced memory B cell dysfunction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCRL4