FBXL18 Antibody (3H5)

Western Blot: FBXL18 Antibody (3H5) [H00080028-M01] - FBXL18 monoclonal antibody (M01), clone 3H5 Analysis of FBXL18 expression in A-431.

Immunohistochemistry-Paraffin: FBXL18 Antibody (3H5) [H00080028-M01] - Analysis of monoclonal antibody to FBXL18 on formalin-fixed paraffin-embedded human salivary gland. Antibody concentration 3 ug/ml.

ELISA: FBXL18 Antibody (3H5) [H00080028-M01] - Detection limit for recombinant GST tagged FBXL18 is approximately 0.1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, IHC, IHC-P, S-ELISA
• Clone: 3H5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

FBXL18 Antibody (3H5) Summary

• Immunogen: FBXL18 (NP_079239, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MASSGEDISNDDDDMHPAAAGMADGVHLLGFSDEILLHILSHVPSTDLILNVRRTCRKLAALCLDKSLIHTVLLQKDYQASEDKVRQLVKEIGREIQQLSMAGCYWLPGS
• Specificity: FBXL18 - F-box and leucine-rich repeat protein 18
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FBXL18
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Sandwich ELISA
• Application Notes: Antibody reactive against cell lysate and recombinant protein for Western Blot. Has also been used for immunohistochemistry (paraffin) and ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for FBXL18 Antibody (3H5)

• Fbl18
• F-box and leucine-rich repeat protein 18FLJ38075
• F-box/LRR-repeat protein 18
• FLJ10776
• FLJ11467
• FLJ26934
• FLJ41541

Background

Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FBXL18
• Entrez:
  • 80028(Human)
• OMIM:
  • 609084(Human)
• Uniprot:
  • NP_079239(Human)