Exosome Component 9 Antibody (1090209) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: IHC, ICC/IF
• Clone: 1090209
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

Exosome Component 9 Antibody (1090209) [Alexa Fluor® 350] Summary

• Immunogen: Synthetic Peptide
  Accession # Q06265
• Specificity: Detects a synthetic peptide specific for hEXOSC9 around amino acid 300 in Direct ELISA.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Exosome Component 9 Antibody (1090209) [Alexa Fluor® 350]

• Autoantigen PM/Scl 1
• EC 3.1.13
• exosome complex component RRP45
• exosome complex exonuclease RRP45
• Exosome Component 9
• p5
• p6
• P75 polymyositis-scleroderma overlap syndrome associated autoantigen
• PCH1D
• PM/Scl-75
• PMSCL autoantigen, 75kD
• PMSCL1
• polymyositis/scleroderma autoantigen 1 (75kD)
• Polymyositis/scleroderma autoantigen 1
• polymyositis/scleroderma autoantigen 1, 75kDa
• RRP45
• Rrp45p

Background

Exosome Component 9 (EXOSC9) is a 49 kDa protein and one of the six core proteins of the RNA exosome complex. It is known that EXOSC9 is necessary for the normal differentiation of epidermal tissues. EXOSC9 is also necessary for P-body formation, stress resistance and tumorigenicity in cancers. Depletion of EXOSC9 attenuates stress resistance and P-body formation in cancer cells and higher EXOSC9 activity correlates with poor prognosis in some types of cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • Q06265(Human)