Exosome component 5 Antibody

Western Blot: Exosome component 5 Antibody [H00056915-B01P] - Analysis of EXOSC5 expression in human kidney.

Immunocytochemistry/Immunofluorescence: Exosome component 5 Antibody [H00056915-B01P] - Analysis of purified antibody to EXOSC5 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: Exosome component 5 Antibody [H00056915-B01P] - Analysis of EXOSC5 expression in transfected 293T cell line by EXOSC5 polyclonal antibody. Lane 1: EXOSC5 transfected lysate(25.85 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

Exosome component 5 Antibody Summary

• Immunogen: EXOSC5 (AAH07742.1, 1 a.a. - 235 a.a.) full-length human protein. MEEEMHTDAKIRAENGTGSSPRGPGCSLRHFACEQNLLSRPDGSASFLQGDTSVLAGVYGPAEVKVSKEIFNKATLEVILRPKIGLPGVAEKSRERLIRNTCEAVVLGTLHPRTSITVVLQVVSDAGSLLACCLNAACMALVDAGVPMRALFCGVACALDSDGTLVLDPTSKQEKEARAVLTFALDSVERKLLMSSTKGLYSDTELQQCLAAAQAASQHVFRFYRESLQRRYSKS
• Specificity: EXOSC5 - exosome component 5,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: EXOSC5
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. It is also useful for immunofluoresence.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Exosome component 5 Antibody

• CML28
• exosome complex exonuclease RRP46
• exosome component 5Chronic myelogenous leukemia tumor antigen 28
• exosome component Rrp46
• hRrp46p
• MGC12901
• p12BMGC111224
• RRP41B
• Rrp46p
• RRP46Ribosomal RNA-processing protein 46

Background

EXOSC5 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAscontaining AU-rich elements (AREs) within their 3'-untranslated regions. Required for the 3'-processing of the 7Spre-RNA to the mature 5.8S rRNA. Has

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EXOSC5
• Entrez:
  • 56915(Human)
• Uniprot:
  • AAH07742.1(Human)