EXOSC3 Antibody

Western Blot: EXOSC3 Antibody [H00051010-B01P] - Analysis of EXOSC3 expression in human pancreas.

Immunocytochemistry/Immunofluorescence: EXOSC3 Antibody [H00051010-B01P] - Analysis of purified antibody to EXOSC3 on HepG2 cell. (antibody concentration 10 ug/ml)

Western Blot: EXOSC3 Antibody [H00051010-B01P] - Analysis of EXOSC3 expression in transfected 293T cell line by EXOSC3 polyclonal antibody. Lane 1: EXOSC3 transfected lysate(30.25 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

EXOSC3 Antibody Summary

• Immunogen: EXOSC3 (NP_057126.2, 1 a.a. - 275 a.a.) full-length human protein. MAEPASVAAESLAGSRARAARTVLGQVVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRLAES
• Specificity: EXOSC3 - exosome component 3,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: EXOSC3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. Has also been used for immunofluorescence.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for EXOSC3 Antibody

• bA3J10.7
• CGI-102
• exosome complex exonuclease RRP40
• exosome component 3MGC15120
• exosome component Rrp40
• hRrp-40
• hRrp40p
• p10Rrp40p
• Ribosomal RNA-processing protein 40
• RP11-3J10.8
• RRP40MGC723

Background

EXOSC3 is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions. Required for the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Ha

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EXOSC3
• Entrez:
  • 51010(Human)
• Uniprot:
  • NP_057126.2(Human)