Ets-1 Antibody

Product Discontinued

Ets-1 Antibody Summary

• Immunogen: The antiserum was produced against synthesized peptide derived from human ETS1. The immunogen region is: N-terminal.
• Localization: Nucleus
• Specificity: ETS1 (Ab-38) Antibody detects endogenous levels of total ETS1 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: ETS1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:1000
  • Immunocytochemistry/ Immunofluorescence 1:100-1:500
  • Immunohistochemistry 1:50-1:100
  • Immunohistochemistry-Paraffin 1:50-1:100
  • Western Blot 1:500-1:1000
• Theoretical MW: 50 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for Ets-1 Antibody

• Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1
• ets protein
• Ets1
• Ets-1
• EWSR2
• FLJ10768
• p54
• Protein C-Ets-1
• v-ets avian erythroblastosis virus E2 oncogene homolog 1
• v-ets avian erythroblastosis virus E26 oncogene homolog 1
• v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
• v-ets

Background

ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Ets-1 Antibody (NBP1-61335)(1)

Publication using NBP1-61335

• Ko JY, Yoo KH, Song SA et al. Inactivation of Max Interacting Protein 1 Induces Renal Cilia Disassembly through Reduction in Levels of Intraflagellar Transport 20 in Polycystic Kidney. J Biol Chem 2013-01-13 [PMID: 23316056] (WB, Mouse)

Bioinformatics

• Gene Symbol: ETS1
• Entrez:
  • 2113(Human)
  • 23871(Mouse)
  • 24356(Rat)
• Uniprot:
  • P14921(Human)