ERp57/PDIA3 Antibody

Western Blot: ERp57/PDIA3 Antibody [H00002923-D01P] - Analysis of PDIA3 expression in mouse liver.

Immunocytochemistry/Immunofluorescence: ERp57/PDIA3 Antibody [H00002923-D01P] - Analysis of antibody to PDIA3 on HeLa cell. Antibody concentration 20 ug/ml.

Western Blot: ERp57/PDIA3 Antibody [H00002923-D01P] - Analysis of PDIA3 expression in HeLa.

Western Blot: ERp57/PDIA3 Antibody [H00002923-D01P] - Analysis of PDIA3 expression in human kidney.

Western Blot: ERp57/PDIA3 Antibody [H00002923-D01P] - Analysis of PDIA3 expression in transfected 293T cell line by PDIA3 polyclonal antibody.Lane 1: PDIA3 transfected lysate(56.80 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

ERp57/PDIA3 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: PDIA3 (NP_005304.3, 1 a.a. - 505 a.a.) full-length human protein. MRLRRLALFPGVALLLAAARLAAASDVLELTDDNFESRISDTGSAGLMLVEFFAPWCGHCKRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRTADGIVSHLKKQAGPASVPLRTEEEFKKFISDKDASIVGFFDDSFSEAHSEFLKAASNLRDNYRFAHTNVESLVNEYDDNGEGIILFRPSHLTNKFEDKTVAYTEQKMTSGKIKKFIQENIFGICPHMTEDNKDLIQGKDLLIAYYDVDYEKNAKGSNYWRNRVMMVAKKFLDAGHKLNFAVASRKTFSHELSDFGLESTAGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQDYFDGNLKRYLKSEPIPESNDGPVKVVVAENFDEIVNNENKDVLIEFYAPWCGHCKNLEPKYKELGEKLSKDPNIVIAKMDATANDVPSPYEVRGFPTIYFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQEDL
• Marker: Endoplasmic Reticulum Marker
• Specificity: Reacts with protein disulfide isomerase family A, member 3.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PDIA3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: This antibody is reactive against tissue and transfected lysate in WB and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ERp57/PDIA3 Antibody

• Disulfide isomerase ER-60
• EC 5.3.4.1
• endoplasmic reticulum P58
• Endoplasmic reticulum resident protein 57
• Endoplasmic reticulum resident protein 60
• ER protein 60
• ER60
• ERp57
• ERp5758 kDa glucose-regulated protein
• ERp60
• ERp6058 kDa microsomal protein
• ERp61
• glucose regulated protein, 58kDa
• GRP57
• GRP58
• GRP58ER protein 57
• HsT17083
• P58
• PDIA3
• phospholipase C-alpha
• PI-PLC
• protein disulfide isomerase family A, member 3
• protein disulfide isomerase-associated 3
• protein disulfide-isomerase A3

Background

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PDIA3
• Entrez:
  • 2923(Human)
• Uniprot:
  • NP_005304.3(Human)