Recombinant Human EN-RAGE/S100A12 Protein

Product Discontinued

Recombinant Human EN-RAGE/S100A12 Protein Summary

• Description: A recombinant protein with GST tag at N-terminal corresponding to the amino acids 33604 of Human S100A12 full-length ORF
  
  

  Source: Wheat Germ (in vitro)

  Amino Acid Sequence:MTKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISLVAIALKAAHYHTHKE

• Details of Functionality: This protein was produced in an in vitro wheat germ expression system that should preserve correct conformational folding that is necessary for biological function. While it is possible that this protein could display some level of activity, the functionality of this protein has not been explicitly measured or validated.
• Source: Wheat germ
• Protein/Peptide Type: Recombinant Protein
• Gene: S100A12
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunoaffinity Purification
  • Protein Array
  • Western Blot
• Theoretical MW: 37 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH 8.0.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant Human EN-RAGE/S100A12 Protein

• CAAF1
• CAAF1Neutrophil S100 protein
• CAAFI
• CAGC
• CAGCS100 calcium binding protein A12 (calgranulin C)
• CAGCS100
• Calcium-binding protein in amniotic fluid 1
• Calgranulin C
• calgranulin-C
• CGRPEN-RAGE
• ENRAGE
• EN-RAGE
• Extracellular newly identified RAGE-binding protein
• MRP6
• p6calgranulin C
• protein S100-A12
• S100 calcium binding protein A12
• S100 calcium-binding protein A12 (calgranulin C)
• S100 calcium-binding protein A12
• S100A12

Background

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: S100A12