Emerin Antibody (EMD/2167) [DyLight 350]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clone
EMD/2167
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 350

Order Details

Emerin Antibody (EMD/2167) [DyLight 350] Summary

Immunogen
Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary)
Localization
Nuclear Membrane
Specificity
Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
EMD
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Emerin Antibody (EMD/2167) [DyLight 350]

  • emerin
  • Emery-Dreifuss muscular dystrophy
  • LEM domain containing 5
  • STAEDMDLEMD5

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Emerin Antibody (NBP2-79918UV) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-79918AF350
Alexa Fluor 405 NBP2-79918AF405
Alexa Fluor 488 NBP2-79918AF488
Alexa Fluor 532 NBP2-79918AF532
Alexa Fluor 594 NBP2-79918AF594
Alexa Fluor 647 NBP2-79918AF647
Alexa Fluor 700 NBP2-79918AF700
Alexa Fluor 750 NBP2-79918AF750
Biotin NBP2-79918B
DyLight 350 NBP2-79918UV
DyLight 405 NBP2-79918V
DyLight 488 NBP2-79918G
DyLight 550 NBP2-79918R
DyLight 594 NBP2-79918DL594
DyLight 650 NBP2-79918C
DyLight 680 NBP2-79918FR
DyLight 755 NBP2-79918IR
FITC NBP2-79918F
HRP NBP2-79918H
Janelia Fluor 549 NBP2-79918JF549
Janelia Fluor 646 NBP2-79918JF646

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Bioinformatics Tool for Emerin Antibody (NBP2-79918UV)

Discover related pathways, diseases and genes to Emerin Antibody (NBP2-79918UV). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

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Blogs on Emerin

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Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

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Bioinformatics

Gene Symbol EMD