Reactivity | HuSpecies Glossary |
Applications | WB, ICC/IF, IHC, IHC-P |
Clone | EMD/2167 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | DyLight 350 |
Immunogen | Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary) |
Localization | Nuclear Membrane |
Specificity | Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma. |
Isotype | IgG1 Kappa |
Clonality | Monoclonal |
Host | Mouse |
Gene | EMD |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Application Notes | Optimal dilution of this antibody should be experimentally determined. |
Storage | Store at 4C in the dark. |
Buffer | 50mM Sodium Borate |
Preservative | 0.05% Sodium Azide |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Alexa Fluor 350 | NBP2-79918AF350 | |
Alexa Fluor 405 | NBP2-79918AF405 | |
Alexa Fluor 488 | NBP2-79918AF488 | |
Alexa Fluor 532 | NBP2-79918AF532 | |
Alexa Fluor 594 | NBP2-79918AF594 | |
Alexa Fluor 647 | NBP2-79918AF647 | |
Alexa Fluor 700 | NBP2-79918AF700 | |
Alexa Fluor 750 | NBP2-79918AF750 | |
Biotin | NBP2-79918B | |
DyLight 350 | NBP2-79918UV | |
DyLight 405 | NBP2-79918V | |
DyLight 488 | NBP2-79918G | |
DyLight 550 | NBP2-79918R | |
DyLight 594 | NBP2-79918DL594 | |
DyLight 650 | NBP2-79918C | |
DyLight 680 | NBP2-79918FR | |
DyLight 755 | NBP2-79918IR | |
FITC | NBP2-79918F | |
HRP | NBP2-79918H | |
Janelia Fluor 549 | NBP2-79918JF549 | |
Janelia Fluor 646 | NBP2-79918JF646 |
Diseases for Emerin Antibody (NBP2-79918UV)Discover more about diseases related to Emerin Antibody (NBP2-79918UV).
| Pathways for Emerin Antibody (NBP2-79918UV)View related products by pathway.
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PTMs for Emerin Antibody (NBP2-79918UV)Learn more about PTMs related to Emerin Antibody (NBP2-79918UV).
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Gene Symbol | EMD |