ELF3/ESE-1 Antibody

Product Discontinued

ELF3/ESE-1 Antibody Summary

• Immunogen: Peptide with sequence C-SGWKEEEVLQSRN corresponding to C-Terminus according to NP_004424.2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ELF3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 2 - 4 ug/ml
• Application Notes: WB: Approx. 48 kDa band observed in NCI-H460 lysate (calculated MW of 41.5 kDa band according to NP_004424.2). In transfected HEK293 transiently expressing ELF3 a band of approx. 40 kDa is observed. This band is not observed in the non-transfected HEK293.
• Control:

  ELF3/ESE-1 Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ELF3/ESE-1 Antibody

• E74-like factor 3 (ets domain transcription factor, epithelial-specific )
• E74-like factor 3
• ELF3
• Epithelial-restricted with serine box
• epithelial-specific)
• Epithelium-restricted Ets protein ESX
• Epithelium-specific Ets transcription factor 1
• EPR1
• EPR-1
• ERT
• ESX
• ets domain transcription factor, serine box (epithelial-specific)
• ETS-related transcription factor Elf-3
• JEN
• serine box

Background

ESE-1 (Epithelium-Specific Ets) is a novel, highly tissue-restricted member of the ets transcription factor/oncogene family, which has features distinct from those of any other ets-related factor. ESE-1 binds with high affinity to and transactivates the ets binding site in the promoter of the keratinocyte terminal differentiation marker gene, SPRR2A. ESE-1 is a critical regulator of epithelial cell differentiation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for ELF3/ESE-1 Antibody (NB100-1061)(1)

Publication using NB100-1061

• Oettgen P, Alani RM, Barcinski MA et al. Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family. Mol Cell Biol 1997-08-01 [PMID: 9234700]

Bioinformatics

• Gene Symbol: ELF3
• Entrez:
  • 1999(Human)
• Uniprot:
  • NP_004424(Human)