DUSP2 Antibody

Western Blot: DUSP2 Antibody [NBP2-14934] - analysis of DUSP2 in HeLa cell lysate using anti-DUSP2 antibody. Image submitted by a verified customer review.

Immunocytochemistry/Immunofluorescence: DUSP2 Antibody [NBP2-14934] - Paraformaldehyde-fixed HeLa, using DUSP2/PAC1 antibody at 1:1000 dilution.

Immunohistochemistry-Paraffin: DUSP2 Antibody [NBP2-14934] - Paraffin-embedded Oral CA, using antibody at 1:100 dilution.

Western Blot: DUSP2 Antibody [NBP2-14934] - Sample (30 ug of whole cell lysate) A: Hela 10% SDS PAGE DUSP2(PAC-1 ) antibody, antibody diluted at 1:1000.

Product Discontinued

DUSP2 Antibody Summary

• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DUSP2/PAC1. The exact sequence is proprietary.
• Predicted Species: Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DUSP2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Application Notes: DUSP2 antibody validated for WB from a verified customer review.
• Theoretical MW: 34 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for DUSP2 Antibody

• dual specificity protein phosphatase 2
• PAC-1
• dual specificity phosphatase 2
• PAC1

Background

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Review for DUSP2 Antibody (NBP2-14934) (1)

Average Rating: 5

(Based on 1 review)

We have 1 review tested in 1 species: Human.

reviewed by: Verified Customer WB Human 10/14/2014

Summary

• Application: Western Blot
• Sample Tested: Cell lysate from HeLa cells
• Species: Human

Bioinformatics

• Gene Symbol: DUSP2
• Uniprot:
  • Q05923(Human)