DUSP2 Products

Antibodies
DUSP2 Antibody
DUSP2 Antibody
NBP2-14934
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
DUSP2 Overexpression Lysate ( ...
DUSP2 Overexpression Lysate (Native)
NBP2-07873
Applications: WB
RNAi
DUSP2 RNAi
DUSP2 RNAi
H00001844-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The protein encoded by the DUSP2 gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 1844
Alternate Names
  • dual specificity protein phosphatase 2
  • PAC1
  • PAC-1
  • dual specificity phosphatase 2

Research Areas for DUSP2

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Signal Transduction

Bioinformatics Tool for DUSP2

Discover related pathways, diseases and genes to DUSP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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