DRAP1 Antibody (PCRP-DRAP1-1A8) [mFluor Violet 610 SE]

• Reactivity: Hu
• Applications: Flow, ICC/IF, IHC
• Clone: PCRP-DRAP1-1A8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

DRAP1 Antibody (PCRP-DRAP1-1A8) [mFluor Violet 610 SE] Summary

• Immunogen: Recombinant human DRAP1 protein
• Localization: Nucleus. Cytoplasm.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: DRAP1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Predicted to react in Mouse, Rat and Chick.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for DRAP1 Antibody (PCRP-DRAP1-1A8) [mFluor Violet 610 SE]

• dr1-associated corepressor
• DR1-associated protein 1 (negative cofactor 2 alpha)
• Dr1-associated protein 1
• NC2-alphaNegative co-factor 2-alpha
• negative cofactor 2 alpha

Background

Transcriptional repression is a general mechanism for regulating transcriptional initiation in organisms ranging from yeast to humans. Accurate initiation of transcription from eukaryotic protein-encoding genes requires the assembly of a large multiprotein complex consisting of RNA polymerase II and general transcription factors such as TFIIA, TFIIB, and TFIID. DR1 is a repressor that interacts with the TATA-binding protein (TBP) of TFIID and prevents the formation of an active transcription complex by precluding the entry of TFIIA and/or TFIIB into the preinitiation complex. The protein encoded by this gene is a corepressor of transcription that interacts with DR1 to enhance DR1-mediated repression. The interaction between this corepressor and DR1 is required for corepressor function and appears to stabilize the TBP-DR1-DNA complex. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DRAP1