DGK-beta Antibody (646523) [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Clone: 646523
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 488

DGK-beta Antibody (646523) [Alexa Fluor™ Plus 488] Summary

• Specificity: Detects human DGK-beta in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human DGK-alpha , gamma , epsilon , iota , kappa , theta , or zeta is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DGK-beta Antibody (646523) [Alexa Fluor™ Plus 488]

• 90 kDa diacylglycerol kinase
• DAG kinase beta
• DAGK2
• DGKB
• DGKbeta
• DGK-beta
• diacylglycerol kinase beta
• diacylglycerol kinase, beta (90kD)
• diacylglycerol kinase, beta 90kDa
• Diglyceride kinase beta
• EC 2.7.1
• EC 2.7.1.107
• KIAA0718DGKDGK-BETA

Background

Diacylglycerol kinase beta (DGK-beta ) is an approximately 90 kDa kinase that phosphorylates the lipid diacylglycerol. It is expressed in the brain and colocalizes with D1 and D2 dopamine receptors. DGK-beta promotes the formation and maturation of dendritic spines. It contains two EF-hand motifs (aa 149-184 and 194-229), two zinc finger regions (aa 244-294 and aa 309-358), and a catalytic domain (aa 434-568). Alternate splicing generates an additional isoform with a 31 aa C-terminal deletion. Over aa 1-143, human DGK-beta shares 97% aa sequence identity with mouse and rat DGK-beta .

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.