Desmoglein-4 Antibody - BSA Free

Images

 
Staining of human skin shows moderate cytoplasmic positivity in keratinocytes.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

Desmoglein-4 Antibody - BSA Free Summary

Description
Novus Biologicals Rabbit Desmoglein-4 Antibody - BSA Free (NBP3-24786) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
This antibody has been engineered to specifically recognize the recombinant protein Desmoglein-4 using the following amino acid sequence: PAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQ
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DSG4
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.2, 40% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for Desmoglein-4 Antibody - BSA Free

  • Cad13
  • Cadherin family member 13
  • CDGF13
  • CDHF13
  • CDHF13CDH family member 13
  • desmoglein 4
  • Desmoglein4
  • Desmoglein-4
  • DSG4
  • LAHdesmoglein-4

Background

DSG4, also known as Desmoglein-4, consists of a 113.8 kDa and a 115.5 kDa isoform and is located in the membrane of desmosomes where it moderates cell to cell adhesion. Diseases and disorders such as impetigo, pemphigus foliaceus, skin disease, prostatitis, hypotrichosis, and monilethrix have been researched with this protein. The protein interacts with other proteins including RAB24, MLST8, and PKP3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol DSG4