Desmoglein-3 Antibody (DSG3/8613R) [Allophycocyanin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
DSG3/8613R
Clonality
Monoclonal
Host
Rabbit
Conjugate
Allophycocyanin

Order Details

Desmoglein-3 Antibody (DSG3/8613R) [Allophycocyanin] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
Recombinant fragment (around aa300-500) of human Desmoglein-3 protein (exact sequence is proprietary)
Localization
Cell surface
Marker
Squamous Cell Marker
Specificity
This monoclonal antibody is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
DSG3
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Desmoglein-3 Antibody (DSG3/8613R) [Allophycocyanin]

  • Cadherin family member 6
  • CDHF6
  • CDHF6130-kD pemphigus vulgaris antigen
  • desmoglein 3 (pemphigus vulgaris antigen)
  • desmoglein 3
  • Desmoglein3
  • Desmoglein-3
  • DKFZp686P23184,130 kDa pemphigus vulgaris antigen
  • DSG3
  • pemphigus vulgaris antigen
  • PVA

Background

Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for Desmoglein-3 Antibody (NBP3-24163APC) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for Desmoglein-3 Antibody (NBP3-24163APC)

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Bioinformatics

Gene Symbol DSG3