delta-Sarcoglycan Antibody (19G8) [CoraFluor™ 1]

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 19G8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

delta-Sarcoglycan Antibody (19G8) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(TM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
  
  CoraFluor(TM) 1, amine reactive
  
  CoraFluor(TM) 1, thiol reactive
  
  For more information, please see our CoraFluor(TM) TR-FRET technology flyer.
• Immunogen: Recombinant human delta-Sarcoglycan (57-289aa) purified from E. coli
• Isotype: IgG1b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SGCD
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for delta-Sarcoglycan Antibody (19G8) [CoraFluor™ 1]

• 35 kDa dystrophin-associated glycoprotein
• 35DAG
• 35kD dystrophin-associated glycoprotein
• CMD1L
• CMD1LSG-delta
• DAGD
• deltaSarcoglycan
• delta-Sarcoglycan
• delta-SG
• dystrophin associated glycoprotein, delta sarcoglycan
• LGMD2F
• MGC22567
• placental delta sarcoglycan
• sarcoglycan, delta (35kD dystrophin-associated glycoprotein)
• sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
• SGCD
• SGCDP
• SGD

Background

delta Sarcoglycan is encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SGCD