DEFB104A Recombinant Protein Summary
A recombinant protein corresponding to 50 amino acids of Human DEFB104A
Source: E. coli
Amino Acid Sequence: The amino acid sequence of this product is not available.
|Details of Functionality
Determined by its ability to chemoattract human monocytes using a concentration range of 0.1-50 ng/ml.
Packaging, Storage & Formulations
Store at -20C. Avoid freeze-thaw cycles.
Centrifuge prior to opening. Reconstitute with sterilized deionized water to a final concentration of at least 0.1 mg/ml.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
The purity of this protein is >95% pure by SDS-PAGE
Alternate Names for DEFB104A Recombinant Protein
- defensin, beta 104A
- defensin, beta 4
Defensins are cationic peptides with a large spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The Alpha defensins are differentiated from the Beta-defensins by the pairing of their 3 disulfide bonds. Four human Beta-defensins have been identified to date; BD-1, BD-2, BD-3 and BD-4. Beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they are chemoattractant towards immature dendritic cells and memory T cells. Beta-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence (for BD-1 a propeptide region). Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Beta Defensin-4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 50 amino acids. The BD-4 is purified by proprietary chromatographic techniques.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed
for 3 months from date of receipt.
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Additional DEFB104A Recombinant Protein Products
Related Products by Gene
, BETA-DEFENSIN 2
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