Cytosolic Sulfotransferase 4A1/SULT4A1 Antibody (634630) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 634630
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

Cytosolic Sulfotransferase 4A1/SULT4A1 Antibody (634630) [Alexa Fluor® 405] Summary

• Immunogen: E. coli-derived recombinant human Cytosolic Sulfotransferase 4A1/SULT4A1
  Ala2-Lys284
  Accession # Q9BR01
• Specificity: Detects human Cytosolic Sulfotransferase 4A1/SULT4A1 in direct ELISAs and Western blots. No cross-reactivity with recombinant human (rh) SULT1A1, rhSULT1A3, rhSULT1B1, rhSULT1E1, rhSULT2A1, or rhSULT2B1 is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Cytosolic Sulfotransferase 4A1/SULT4A1 Antibody (634630) [Alexa Fluor® 405]

• Brain sulfotransferase-like protein
• BRSTL1
• BR-STL-1
• Cytosolic Sulfotransferase 4A1
• EC 2.8.2.-
• hBR-STL
• hBR-STL-1MGC40032
• nervous system cytosolic sulfotransferase
• Nervous system sulfotransferase
• NST
• ST4A1
• sulfotransferase 4A1
• sulfotransferase family 4A, member 1
• sulfotransferase-related protein
• SULT4A1
• SULTX3
• SULTX3DJ388M5.3

Background

Cytosolic SULT4A1 (Sulfotransferase 4A1 also BR-STL1/Brain sulfotransferase-like protein) is a 33-36 kDa member of the sulfotransferase 4 family of enzymes.  SULT4A1 message is widely expressed.  However, it appears to be translated only in brain.  SULT4A is very unusual in that it is the only SULT that shows minimal activity on synthetic laboratory substrates.  Instead, it acts on catecholamines and T4 in a manner that may not involve sulfonation.  Human SULT4A1 is 284 amino acids (aa) in length.  A weak PAPS binding site is found between aa 246-254.  There are two potential isoforms, one that shows a 13 aa substitution for aa 248-284, and a second that contains a 48 aa substitution for aa 202-247.  Full length human SULT4A1 is 98% aa identical to mouse SULT4A1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • Q9BR01()