Cytosolic Sulfotransferase 4A1/SULT4A1 Antibody (634630) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 634630
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Cytosolic Sulfotransferase 4A1/SULT4A1 Antibody (634630) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human Cytosolic Sulfotransferase 4A1/SULT4A1
  Ala2-Lys284
  Accession # Q9BR01
• Specificity: Detects human Cytosolic Sulfotransferase 4A1/SULT4A1 in direct ELISAs and Western blots. No cross-reactivity with recombinant human (rh) SULT1A1, rhSULT1A3, rhSULT1B1, rhSULT1E1, rhSULT2A1, or rhSULT2B1 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Cytosolic Sulfotransferase 4A1/SULT4A1 Antibody (634630) [Alexa Fluor® 488]

• Brain sulfotransferase-like protein
• BRSTL1
• BR-STL-1
• Cytosolic Sulfotransferase 4A1
• EC 2.8.2.-
• hBR-STL
• hBR-STL-1MGC40032
• nervous system cytosolic sulfotransferase
• Nervous system sulfotransferase
• NST
• ST4A1
• sulfotransferase 4A1
• sulfotransferase family 4A, member 1
• sulfotransferase-related protein
• SULT4A1
• SULTX3
• SULTX3DJ388M5.3

Background

Cytosolic SULT4A1 (Sulfotransferase 4A1 also BR-STL1/Brain sulfotransferase-like protein) is a 33-36 kDa member of the sulfotransferase 4 family of enzymes.  SULT4A1 message is widely expressed.  However, it appears to be translated only in brain.  SULT4A is very unusual in that it is the only SULT that shows minimal activity on synthetic laboratory substrates.  Instead, it acts on catecholamines and T4 in a manner that may not involve sulfonation.  Human SULT4A1 is 284 amino acids (aa) in length.  A weak PAPS binding site is found between aa 246-254.  There are two potential isoforms, one that shows a 13 aa substitution for aa 248-284, and a second that contains a 48 aa substitution for aa 202-247.  Full length human SULT4A1 is 98% aa identical to mouse SULT4A1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.