Cytohesin 2 Antibody

Images

 
Western Blot: Cytohesin 2 Antibody [H00009266-D01P] - Analysis of CYTH2 expression in transfected 293T cell line by CYTH2 polyclonal antibody.Lane 1: CYTH2 transfected lysate(46.50 KDa).Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: Cytohesin 2 Antibody [H00009266-D01P] - Analysis of antibody to CYTH2 on HeLa cell. Antibody concentration 10 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Cytohesin 2 Antibody Summary

Immunogen
PSCD2 (NP_059431.1, 1 a.a. ~ 400 a.a) full-length human protein.MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEANEGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPEDDGNDLTH
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CYTH2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.
Theoretical MW
72 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cytohesin 2 Antibody

  • ARF exchange factor
  • ARF nucleotide-binding site opener
  • ARNOPH, SEC7 and coiled-coil domain-containing protein 2
  • CTS18.1
  • cytohesin 2
  • pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)
  • Protein ARNO
  • PSCD2LCTS18
  • PSCD2pleckstrin homology, Sec7 and coiled-coil domains 2
  • Sec7 and coiled/coil domains 2 (cytohesin-2)

Background

The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83% homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CYTH2
Entrez
Uniprot