Cyr61/CCN1 Recombinant Protein



Product Details

Reactivity HuSpecies Glossary
Applications WB, ELISA, PA
Please see the vial label for concentration. If unlisted please contact technical services.

Order Details

Cyr61/CCN1 Recombinant Protein Summary

Cyr61/CCN1 (Human) GST-Tagged Recombinant Protein

Source: Wheat Germ (in vitro)


Packaging, Storage & Formulations

Store at -80C. Avoid freeze-thaw cycles.
50 mM Tris-HCl, 10 mM reduced Glutathione, pH 8.0 in the elution buffer.
Please see the vial label for concentration. If unlisted please contact technical services.


Application Notes
Useful in Western Blot and ELISA. This protein has not been tested for any functionality. This product may contain endotoxins and is not suitable for use with live cells.
Read Publications using H00003491-P01.

Reactivity Notes



This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Cyr61/CCN1 Recombinant Protein

  • CCN family member 1
  • CCN1
  • CCN1IGF-binding protein 10
  • Cysteine-rich angiogenic inducer 61
  • cysteine-rich, angiogenic inducer, 61
  • GIG1
  • GIG1cysteine-rich heparin-binding protein 61
  • IBP-10
  • IGFBP-10
  • IGFBP10cysteine-rich, anigogenic inducer, 61
  • Insulin-like growth factor-binding protein 10
  • protein CYR61
  • Protein GIG1


CYR61( AAH01271, 1 a.a. - 382 a.a.) recombinant protein with GST.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Publications for Cyr61/CCN1 Recombinant Protein (H00003491-P01)(16)

Showing Publications 1 - 10 of 16. Show All 16 Publications.
Publications using H00003491-P01 Applications Species
Jeansonne D, Pacifici M, Lassak A et al. Differential Effects of MicroRNAs on Glioblastoma Growth and Migration. Genes. 2013 Mar 4 [PMID:24705102]
You JJ, Yang CH, Yang CM, Chen MS. Cyr61 induces the expression of monocyte chemoattractant protein-1 via the integrin avb3, FAK, PI3K/Akt, and NF-kB pathways in retinal vascular endothelial cells. Cell Signal. 2013 Sep 22 [PMID:24063814]
Kok SH, Lin LD, Hou KL et al. Simvastatin inhibits Cyr61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of SIRT1/FoxO3a signaling. Arthritis Rheum. 2012 Dec 12 [PMID:23239110]
Wu PH, Lin SK, Lee BS et al. Epigallocatechin-3-gallate diminishes cytokine-stimulated Cyr61 expression in human osteoblastic cells: a therapeutic potential for arthritis. Rheumatology (Oxford). 2012 Jun 11 [PMID:22843790]
Terada N, Shiraishi T, Zeng Y et al. Cyr61 is regulated by cAMP-dependent protein kinase with serum levels correlating with prostate cancer aggressiveness. Prostate. 2011 Oct 24 [PMID:22025384]
You JJ, Yang CM, Chen MS, Yang CH. Regulation of Cyr61/CCN1 expression by hypoxia through cooperation of c-Jun/AP-1 and HIF-1? in retinal vascular endothelial cells. Exp Eye Res. 2010 Oct 26 [PMID:21029732]
Su JL, Chiou J, Tang CH et al. CYR61 regulates BMP-2-dependent osteoblast differentiation through {alpha}v{beta}3 integrin/ILK/ERK pathway. J Biol Chem. 2010 Jul 30 [PMID:20675382]
Chai J, Norng M, Modak C et al. CCN1 induces a reversible epithelial-mesenchymal transition in gastric epithelial cells. Lab Invest. 2010 May 10. [PMID:20458273]
Kok SH, Hou KL, Hong CY et al. Simvastatin inhibits cytokine-stimulated Cyr61 expression in osteoblastic cells: A therapeutic benefit for arthritis. Arthritis Rheum. 2010 Feb 26. [PMID:20191585]
Bar A, Dorfman SE, Fischer P et al. The pro-angiogenic factor CCN1 enhances the re-endothelialization of biological vascularized matrices in vitro. Cardiovasc Res. 2009 Dec 16. [PMID:19920130]
Show All 16 Publications.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Contact Information

Product PDFs


Gene Symbol CYR61

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