CSE1L/CAS/Exportin-2 Antibody (5111)

Images

 
Genetic Strategies: Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609] - Non-transfected (-) and transfected (+) 293T whole cell extracts (15 ug) were separated by 7.5% SDS-PAGE, and the membrane was ...read more
Immunocytochemistry/ Immunofluorescence: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609] - CSE1L Antibody (5111) detects CSE1L protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% ...read more
Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609] - Analysis of A. 30 ug 293T whole cell lysate/extract B. 30 ug A431 whole cell lysate/extract C. 30 ug HeLa whole cell lysate/extract D. 30 ug HepG2 whole ...read more
Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609] - Analysis of A. 30 ug Neuro2A whole cell lysate/extract B. 30 ug GL261 whole cell lysate/extract C. 30 ug C8D30 whole cell lysate/extract D. 30 ug NIH-3T3 ...read more
Western Blot: CSE1L/CAS/Exportin-2 Antibody (5111) [NBP2-43609] - Analysis of A. 30 ug PC-12 whole cell lysate/extract B. 30 ug Rat2 whole cell lysate/extract 7.5 % SDS-PAGE CSE1L antibody [5111] dilution: 1:1000.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, RM, Xp, ZeSpecies Glossary
Applications WB, ICC/IF
Clone
5111
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Validated by:
     

Genetic Strategies

   

Order Details

CSE1L/CAS/Exportin-2 Antibody (5111) Summary

Immunogen
Recombinant protein encompassing a sequence within the center region of human CSE1L. The exact sequence is proprietary.
Predicted Species
Porcine (100%), Bovine (100%), Rhesus Macaque (100%), Zebrafish (95%), Xenopus (97%). Backed by our 100% Guarantee.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
CSE1L
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence 1:100-1:1000
  • Western Blot 1:500-1:3000

Reactivity Notes

Xenopus laevis (97%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Purity
Protein G purified

Alternate Names for CSE1L/CAS/Exportin-2 Antibody (5111)

  • CAS
  • CASMGC117283
  • Cellular apoptosis susceptibility protein
  • chromosome segregation 1 (yeast homolog)-like
  • Chromosome segregation 1-like protein
  • CSE1 chromosome segregation 1-like (yeast)
  • CSE1
  • CSE1L
  • exp2
  • exportin-2
  • Importin-alpha re-exporter
  • MGC130037
  • XPO2
  • XPO2MGC130036

Background

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CSE1L