CRYBA4 Antibody - BSA Free

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Immunohistochemistry-Paraffin: CRYBA4 Antibody [NBP2-57040] - Staining of eye shows strong positivity in the lens.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

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Catalog# & Formulation Size Price

CRYBA4 Antibody - BSA Free Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: MTLQCTKSAGPWKMVVWDEDGFQG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRYBA4
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
CRYBA4 Recombinant Protein Antigen (NBP2-57040PEP)

Reactivity Notes

Mouse 88%, Rat 83%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for CRYBA4 Antibody - BSA Free

  • Beta-A4 crystallin
  • beta-crystallin A4
  • crystallin, beta A4
  • crystallin, beta polypeptide A4
  • eye lens structural protein
  • MCOPCT4

Background

CRYBA4, or Beta-crystallin A4, consists of a 196 amino acid isoform that is 22 kDa, and is involved in maintaining the structure, transparency, and refractive index of the eye lens. Current disease research has linked defects in CRYBA4 to several types of cataracts, including lamellar 2 cataracts, zonular cataract, congenital cataracts, and microphthalmia cataract. Researchers are also studying the relation between the protein and the disorders choroididits and neurofibromatosis. CRYBA4 is included in several biological processes, including visual perception and camera-type eye development, through which it interacts with CRYBB2 and CRYBB3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CRYBA4