CRMP4 Antibody (SR2081) - BSA Free

Western Blot: CRMP4 Antibody (SR2081) [NBP3-22288] - Western blot analysis using NBP3-22288 in Human fetal brain lysate.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, IP
• Clone: SR2081
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

CRMP4 Antibody (SR2081) - BSA Free Summary

• Description: Novus Biologicals Rabbit CRMP4 Antibody (SR2081) - BSA Free (NBP3-22288) is a recombinant monoclonal antibody validated for use in WB, ICC/IF and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthesized peptide derived from human CRMP4 (Uniprot #: Q14195)
• Specificity: Detects endogenous levels of total CRMP4
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: DPYSL3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunoprecipitation 1:50
  • Western Blot 1:500-1:2000
• Theoretical MW: 62 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH 7.4, 150mM NaCl, 50% glycerol.
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for CRMP4 Antibody (SR2081) - BSA Free

• Collapsin response mediator protein 4
• CRMP-4
• CRMP4collapsin response mediator protein 4 long
• dihydropyrimidinase-like 3
• DRP-3dihydropyrimidinase-related protein 3
• DRP3ULIP1
• ULIP-1
• ULIPLCRMP
• Unc-33-like phosphoprotein 1

Background

The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DPYSL3