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CRB1 Antibody [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 450 SE

Order Details

CRB1 Antibody [mFluor Violet 450 SE] Summary

Immunogen
Antibody was raised against an 18 amino acid peptide near the center of human CRB1. The immunogen is located within amino acids 780 - 830 of CRB1. Amino Acid Squence: ISLKIKPYKIELYQSSQ
Specificity
Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRB1
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Peptide affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for CRB1 Antibody [mFluor Violet 450 SE]

  • crumbs homolog 1 (Drosophila)
  • LCA8

Background

CRB1, also known as Protein crumbs homolog 1, contains several isoforms that are 154 kDa, 151 kDa, 142 kDa, 104 kDa, and 95 kDa, and is involved in the development of photoreceptors in the retina. Defects and mutations in the CRB1 protein result in a variety of disorders, and more research is currently being conducted on the protein's relation to other diseases, including pigmented paravenous chorioretinal atrophy, cone-rod dystrophy, Stargardt disease, keratoconus, retinal degeneration, hyperopia, tuberous sclerosis, and blindness. The protein is linked to epithelial tight junction pathways, and interacts with INADL, MPP5, PSMD13, PRKAR1A, and DDX56.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional CRB1 Products

Array NBP2-41201MFV450

Research Areas for CRB1 Antibody (NBP2-41201MFV450)

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Blogs on CRB1

There are no specific blogs for CRB1, but you can read our latest blog posts.
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Bioinformatics

Gene Symbol CRB1