Connexin 45/GJC1 Antibody (5B9.2) [mFluor Violet 450 SE]

• Reactivity: Hu, Rt, Rb, Mu, Ca
• Applications: WB, ICC/IF
• Clone: 5B9.2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

Connexin 45/GJC1 Antibody (5B9.2) [mFluor Violet 450 SE] Summary

• Immunogen: The peptide sequence used for the immunogen was H-Gln-Ala-Tyr-Ser-His-Gln-Asn-Asn-Pro-His-Gly-Pro-Arg-Glu-Cys-OH conjugated to KLH, corresponding to amino acids 354-377 of human connexin 45.
• Predicted Species: Mouse (92%), Canine (100%). Backed by our 100% Guarantee.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: GJC1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Due to sequence homologies, this antibody is also expected to react with canine (100% homology) and mouse (92% homology) Connexin 45. Also confirmed to work on rat C6 cells. Others not tested.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Connexin 45/GJC1 Antibody (5B9.2) [mFluor Violet 450 SE]

• Connexin 45
• connexin-45
• CX45
• DKFZp686P0738
• Gap junction alpha-7 protein
• gap junction gamma-1 protein
• gap junction protein, alpha 7, 45kDa
• gap junction protein, gamma 1, 45kDa
• GJA7
• GJC1

Background

One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GJC1