Connexin 26/GJB2 Antibody - BSA Free

Western Blot: Connexin 26/GJB2 Antibody - BSA Free [NBP3-47559] - Human heart tissue were subjected to SDS PAGE followed by western blot with (Connexin 26/GJB2 antibody) at dilution of 1:500

Immunohistochemistry: Connexin 26/GJB2 Antibody - BSA Free [NBP3-47559] - Immunohistochemistry of paraffin-embedded human colon cancer using (Connexin 26/GJB2 antibody) at dilution of 1:50

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Connexin 26/GJB2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Connexin 26/GJB2 Antibody - BSA Free (NBP3-47559) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: gap junction protein, beta 2, 26kDa. (Uniprot# P29033)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GJB2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:200-1:1000
• Theoretical MW: 26 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Connexin 26/GJB2 Antibody - BSA Free

• beta 2, 26kD (connexin 26)
• Connexin 26
• CX26
• CX26DFNA3
• DFNA3
• DFNA3A
• DFNB1
• gap junction protein, beta 2, 26kDa (connexin 26)
• gap junction protein, beta 2, 26kDa
• GJB2
• HID
• KID
• NSRD1
• PPK

Background

Connexin-26 / GJB2 is a gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighboring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-26 belongs to the class 1 (beta) group of connexins. Mutations in Connexin-26 are associated with genetically derived hearing impairments, including autosomal recessive non syndromic deafness.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GJB2