Rat reactivity reported in scientific literature (PMID: 8924759)
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified
Alternate Names for Complement Factor I Antibody (OX-21) - BSA Free
AHUS3
C3b Inactivator
C3B/C4B inactivator
C3BINA
C3b-inactivator
CFI
complement component I
complement control protein factor I
complement factor I heavy chain
Complement Factor I
EC 3.4.21
EC 3.4.21.45
FIC3b-INA
I factor (complement)
IF
KAF
Konglutinogen-activating factor
light chain of factor I
Background
Factor I is a plasma protein of molecular weight 88 kDa, consisting of two disulphide linked chains of 50 and 38 kDa. Factor I is a serine protease with a high degree of specificity for C3b and C4b. It has a requirement for protein cofactors for cleavage of these complement proteins, Factor H, CR1 or MCP are required for C3b cleavage and C4bp or CR1 for C4b cleavage.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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