Collagen XXV alpha 1 Antibody

Western Blot: Collagen XXV alpha 1 Antibody [H00084570-B01P] - Analysis of COL25A1 expression in human placenta.

Western Blot: Collagen XXV alpha 1 Antibody [H00084570-B01P] - Analysis of COL25A1 expression in transfected 293T cell line by COL25A1 polyclonal antibody. Lane 1: COL25A1 transfected lysate(54.56 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

Collagen XXV alpha 1 Antibody Summary

• Immunogen: COL25A1 (AAH36669.1, 1 a.a. - 496 a.a.) full-length human protein. MLLKKHAGKGGGREPRSEDPTPAEQHCARTMPPCAVLAALLSVVAVVSCLYLGVKTNDLQARIAALESAKGAPSIHLLPDTLDHLKTMVQEKVERLLAQKSYEHMAKIRIAREAPSECNCPAGPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRGPLGPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGTKGEQGSPGIPGMDGEQGLKGSKGDMGDPGSQWNERRKRRFWNAGSTGSFYHRPTRPTRSPWPTWPHGTSWTSWTKGSIWLRRKARIPGYRWSYGTPWPCRSQRRKR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: COL25A1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Collagen XXV alpha 1 Antibody

• Alzheimer disease amyloid-associated protein
• AMY
• CLAC
• CLACP
• CLAC-P
• COL25A1
• Collagen 25
• collagen alpha-1(XXV) chain
• Collagen XXV alpha 1
• collagen, type XXV, alpha 1
• Collagen-25
• collagen-like Alzheimer amyloid plaque component
• collagenous Alzheimer amyloid plaque component

Background

Antibodies against senile plaque (SP) amyloid obtained a clone which labeled amyloid fibrils in SPs and reacted with approximately 50/100 kDa polypeptides in Alzheimer's disease (AD) brains. The antigen was identified as CLAC (collagen-like Alzheimer amyloid plaque component), and its precursor as CLAC-P/collagen type XXV. Both secreted and membrane-tethered forms of CLAC-P/collagen type XXV specifically bound to fibrillized Abeta, implicating these proteins in beta-amyloidogenesis and neuronal degeneration in AD.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: COL25A1
• Uniprot:
  • AAH36669.1(Human)